Nintedanib ethanesulfonate crystal
The invention relates to a nintedanib ethanesulfonate crystal. Specifically, the invention relates to a type A crystal of nintedanib diethanesulfonate. The the X-ray powder diffraction spectrum of the nintedanib diethanesulfonate type A crystal provided by the invention is shown by a 2theta value to...
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| creator | ZHU XUEYAN SUN JIUDE ZHANG JIASONG GUO MENG HU MINGTONG WANG HUBO |
| description | The invention relates to a nintedanib ethanesulfonate crystal. Specifically, the invention relates to a type A crystal of nintedanib diethanesulfonate. The the X-ray powder diffraction spectrum of the nintedanib diethanesulfonate type A crystal provided by the invention is shown by a 2theta value to have diffraction peaks at about 14.64, 18.79, 19.31, 20.11, 21.20, 22.45 and 26.71 degrees. The crystal provided by the invention has the characteristics of stable properties, difficult degradation, and no absorption of moisture, and is especially suitable for production of drugs.
本发明涉及尼达尼布乙磺酸盐结晶，具体而言，本发明涉及尼达尼布二乙磺酸盐的A型结晶。本发明的尼达尼布二乙磺酸盐A型结晶，其X-射线粉末衍射光谱用2θ值表示在约14.64、18.79、19.31、20.11、21.20、22.45、26.71°处有衍射峰。本发明的结晶性质稳定，不易降解、不吸潮，特别适合药物生产。 |
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本发明涉及尼达尼布乙磺酸盐结晶，具体而言，本发明涉及尼达尼布二乙磺酸盐的A型结晶。本发明的尼达尼布二乙磺酸盐A型结晶，其X-射线粉末衍射光谱用2θ值表示在约14.64、18.79、19.31、20.11、21.20、22.45、26.71°处有衍射峰。本发明的结晶性质稳定，不易降解、不吸潮，特别适合药物生产。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161012&DB=EPODOC&CC=CN&NR=106008308A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161012&DB=EPODOC&CC=CN&NR=106008308A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHU XUEYAN</creatorcontrib><creatorcontrib>SUN JIUDE</creatorcontrib><creatorcontrib>ZHANG JIASONG</creatorcontrib><creatorcontrib>GUO MENG</creatorcontrib><creatorcontrib>HU MINGTONG</creatorcontrib><creatorcontrib>WANG HUBO</creatorcontrib><title>Nintedanib ethanesulfonate crystal</title><description>The invention relates to a nintedanib ethanesulfonate crystal. Specifically, the invention relates to a type A crystal of nintedanib diethanesulfonate. The the X-ray powder diffraction spectrum of the nintedanib diethanesulfonate type A crystal provided by the invention is shown by a 2theta value to have diffraction peaks at about 14.64, 18.79, 19.31, 20.11, 21.20, 22.45 and 26.71 degrees. The crystal provided by the invention has the characteristics of stable properties, difficult degradation, and no absorption of moisture, and is especially suitable for production of drugs.
本发明涉及尼达尼布乙磺酸盐结晶，具体而言，本发明涉及尼达尼布二乙磺酸盐的A型结晶。本发明的尼达尼布二乙磺酸盐A型结晶，其X-射线粉末衍射光谱用2θ值表示在约14.64、18.79、19.31、20.11、21.20、22.45、26.71°处有衍射峰。本发明的结晶性质稳定，不易降解、不吸潮，特别适合药物生产。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFDyy8wrSU1JzMtMUkgtyUjMSy0uzUnLz0ssSVVILqosLknM4WFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8c5-hgZmBgYWxgYWjsbEqAEA5l8mgQ</recordid><startdate>20161012</startdate><enddate>20161012</enddate><creator>ZHU XUEYAN</creator><creator>SUN JIUDE</creator><creator>ZHANG JIASONG</creator><creator>GUO MENG</creator><creator>HU MINGTONG</creator><creator>WANG HUBO</creator><scope>EVB</scope></search><sort><creationdate>20161012</creationdate><title>Nintedanib ethanesulfonate crystal</title><author>ZHU XUEYAN ; SUN JIUDE ; ZHANG JIASONG ; GUO MENG ; HU MINGTONG ; WANG HUBO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN106008308A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHU XUEYAN</creatorcontrib><creatorcontrib>SUN JIUDE</creatorcontrib><creatorcontrib>ZHANG JIASONG</creatorcontrib><creatorcontrib>GUO MENG</creatorcontrib><creatorcontrib>HU MINGTONG</creatorcontrib><creatorcontrib>WANG HUBO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHU XUEYAN</au><au>SUN JIUDE</au><au>ZHANG JIASONG</au><au>GUO MENG</au><au>HU MINGTONG</au><au>WANG HUBO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Nintedanib ethanesulfonate crystal</title><date>2016-10-12</date><risdate>2016</risdate><abstract>The invention relates to a nintedanib ethanesulfonate crystal. Specifically, the invention relates to a type A crystal of nintedanib diethanesulfonate. The the X-ray powder diffraction spectrum of the nintedanib diethanesulfonate type A crystal provided by the invention is shown by a 2theta value to have diffraction peaks at about 14.64, 18.79, 19.31, 20.11, 21.20, 22.45 and 26.71 degrees. The crystal provided by the invention has the characteristics of stable properties, difficult degradation, and no absorption of moisture, and is especially suitable for production of drugs.
本发明涉及尼达尼布乙磺酸盐结晶，具体而言，本发明涉及尼达尼布二乙磺酸盐的A型结晶。本发明的尼达尼布二乙磺酸盐A型结晶，其X-射线粉末衍射光谱用2θ值表示在约14.64、18.79、19.31、20.11、21.20、22.45、26.71°处有衍射峰。本发明的结晶性质稳定，不易降解、不吸潮，特别适合药物生产。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Nintedanib ethanesulfonate crystal |
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