Apixaban tablet

The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to an apixaban tablet. The apixaban tablet contains apixaban, hydroxy propyl cellulose and fumed silica. A preparation method of the apixaban tablet comprises the following steps: dissolving apixaban and hydroxy propyl cellulose in diethylene glycol monoethyl ether, adding with fumed silica for adsorption, then uniformly mixing with pharmaceutically acceptable auxiliary materials, and carrying out pressing by adopting a direct tableting technology. Compared with the prior art, the apixaban tablet has the advantages that the medicine dissolution speed is high, the process is simple, a surfactant does not need to be added, and the micronization treatment is not needed. The acceleration test result shows that the prepared apixaban tablet is good in stability. 本发明属于医药制剂技术领域，具体涉及种阿哌沙班片剂。所述阿哌沙班片剂，含有阿哌沙班、羟丙基纤维素、气相二氧化硅，将阿哌沙班、羟丙基纤维素溶解在二乙二醇单乙基醚中，加入气相二氧化硅吸附，然后和药学上可接受的辅料混合均匀，采用直接压片工艺压制而成。本发明与现有技术相比，药物溶出速度快，工艺简单，不需要添加表面活