Use of 12-dehydroabietic acid oxime ether derivative

The invention relates to a use of a 12-dehydroabietic acid oxime ether derivative. The 12-dehydroabietic acid oxime ether derivative has good inhibition activity on Staphylococcus aureus newman strains, and also has certain inhibition activity on some drug-resistant strains, such as NRS-1 strains (...

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Hauptverfasser: WANG TIANQI, YANG CAIGUANG, LIN HAIXIA, PAN XUEYING, ZHANG WENMING, CUI YONGMEI
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creator WANG TIANQI
YANG CAIGUANG
LIN HAIXIA
PAN XUEYING
ZHANG WENMING
CUI YONGMEI
description The invention relates to a use of a 12-dehydroabietic acid oxime ether derivative. The 12-dehydroabietic acid oxime ether derivative has good inhibition activity on Staphylococcus aureus newman strains, and also has certain inhibition activity on some drug-resistant strains, such as NRS-1 strains ( aminoglycoside antibiotic and tetracycline resistant Staphylococcus aureus), NRS-70 strains (erythromycin and spectinomycin resistant Staphylococcus aureus), NRS-100 strains (oxacillin and tetracycline resistant Staphylococcus aureus), NRS-108 strains (gentamycin resistant Staphylococcus aureus) and NRS-271 strains (methicillin and linezolid resistant Staphylococcus aureus). 本发明涉及种12-肟醚脱氢枞酸衍生物的用途。12-肟醚脱氢枞酸衍生物对金黄色葡萄球菌newman菌株有较好的抑制活性,同时对些耐药菌株如NRS-1菌株(耐氨基糖苷类抗生素和四环素的金黄色葡萄球菌)、NRS-70菌株(耐红霉素和奇放线菌素的金黄色葡萄球菌)、NRS-100 菌株(耐苯唑青霉素和四环素的金黄色葡萄球菌)、NRS-108 菌株(耐庆大霉素的金黄色葡萄球菌)、NRS-271 菌株(耐甲氧西林和利奈唑胺的金黄色葡萄球菌)均有定程度的抑制活性。
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Use of 12-dehydroabietic acid oxime ether derivative
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