Use of 12-dehydroabietic acid oxime ether derivative

The invention relates to a use of a 12-dehydroabietic acid oxime ether derivative. The 12-dehydroabietic acid oxime ether derivative has good inhibition activity on Staphylococcus aureus newman strains, and also has certain inhibition activity on some drug-resistant strains, such as NRS-1 strains (...

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Bibliographische Detailangaben
Hauptverfasser:	WANG TIANQI, YANG CAIGUANG, LIN HAIXIA, PAN XUEYING, ZHANG WENMING, CUI YONGMEI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a use of a 12-dehydroabietic acid oxime ether derivative. The 12-dehydroabietic acid oxime ether derivative has good inhibition activity on Staphylococcus aureus newman strains, and also has certain inhibition activity on some drug-resistant strains, such as NRS-1 strains ( aminoglycoside antibiotic and tetracycline resistant Staphylococcus aureus), NRS-70 strains (erythromycin and spectinomycin resistant Staphylococcus aureus), NRS-100 strains (oxacillin and tetracycline resistant Staphylococcus aureus), NRS-108 strains (gentamycin resistant Staphylococcus aureus) and NRS-271 strains (methicillin and linezolid resistant Staphylococcus aureus). 本发明涉及种12-肟醚脱氢枞酸衍生物的用途。12-肟醚脱氢枞酸衍生物对金黄色葡萄球菌newman菌株有较好的抑制活性，同时对些耐药菌株如NRS-1菌株(耐氨基糖苷类抗生素和四环素的金黄色葡萄球菌)、NRS-70菌株(耐红霉素和奇放线菌素的金黄色葡萄球菌)、NRS-100 菌株(耐苯唑青霉素和四环素的金黄色葡萄球菌)、NRS-108 菌株(耐庆大霉素的金黄色葡萄球菌)、NRS-271 菌株(耐甲氧西林和利奈唑胺的金黄色葡萄球菌)均有定程度的抑制活性。