Application of loganin in preparation of drugs or health care products for improving sleep

Belonging to the field of compound drugs, the invention relates to pharmaceutical new use of loganin, especially the use of loganin in preparation of drugs or health care products for improving sleep. The loganin provided by the invention is one of the main chemical components of Cornaceae plant cornus officinalis, the chemical formula is C17H26O10, and the molecular weight is 390.38. Animal experiments confirm that loganin can significantly prolong the total sleep time of mice, and has the characteristic of dose dependent increase of sleep amount. Preliminary action mechanism study shows that loganin possibly induces sleep by increasing the level of 5-HT in mouse brain. To sum up, loganin can be prepared into drugs and health care products with sedative and hypnotic effects, the made dosage forms include granules, tablets, capsules, granules, electuaries, oral liquid, dripping pills, pellets or injections. 本发明属于化合物药物领域，涉及马钱苷的药物新用途，尤其是马钱苷在制备改善睡眠的药物或保健品中的用途。本发明提供的马钱苷(Loganin)系山茱萸科植物山茱萸(Cornus officinalis)的主要化学