Novel application of Pinghuwanxing sesquiterpene compound of nardostachys chinensis batal

The invention provides a novel application of a Pinghuwanxing sesquiterpene compound, namely Isonardosinone or kanshone E, of nardostachys chinensis batal.; the Pinghuwanxing sesquiterpene compound of the nardostachys chinensis batal. is obtained from rhizome of the nardostachys chinensis batal., wh...

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Hauptverfasser: Ying Shusong, Zhu Yan, Xu Yantong, Chen Yingpeng, Dong Pengzhi, Wu Honghua, Liu Yanting, Zhang Peng
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a novel application of a Pinghuwanxing sesquiterpene compound, namely Isonardosinone or kanshone E, of nardostachys chinensis batal.; the Pinghuwanxing sesquiterpene compound of the nardostachys chinensis batal. is obtained from rhizome of the nardostachys chinensis batal., which belongs to valerianaceae nardostachys plants, by separating and purifying; the sesquiterpene compound has a 5-serotonin transporter (SERT) enhanced activity; the sesquiterpene compound, as a rare SERT activity promoter, is applicable to preparing medicines for treating such neuropsychiatric diseases as depression, anxiety disorder, schizophrenia, obsessive-compulsive disorder, neurodegenerative disease, drug addiction and the like as well as medicines for treating such digestive system dysfunction diseases as slow transit constipation, irritable bowel syndrome, functional abdominal distention and the like; and the sesquiterpene compound has an important medicine development value. 本发明提供了甘松萍瑚烷型倍半萜化合物异甘松新酮或甘松香酮E的