Cold-chain transportation cold preservation box and manufacturing method thereof

The invention provides a cold-chain transportation cold preservation box and a manufacturing method thereof, wherein the cold-chain transportation cold preservation box comprises a box body and a box cover; the box body is provided with an opening, and each of the box body and the box cover comprises an outer layer, a thermal insulating layer and an inner layer; the box cover can be detachably connected with the box body and is used for closing the opening; and each thermal insulating layer is made of an aerogel thermal insulating material and is arranged between each outer layer and each inner layer. According to the cold-chain transportation cold preservation box provided by the invention, the thermal insulating layer made of the aerogel thermal insulating material has an ultralow thermal conductivity, is good in low-temperature stability and can keep cold preservation performance, favorable flexibility and non-cracking property for a long term at 270 DEG C below zero; compared with a thermal insulation box