Subsituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heterapahanes and meatllocenes useful for treating HCV infections

The present disclosure provides substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes, of Formula (I) D-M-D (Formula I) useful as antiviral agents. In certain embodiments disclosed herein M is a group -P-A-P- where A is the Formula (I). Certain substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes disclosed herein are potent and/or selective inhibitors of viral replication, particularly Hepatitis C virus replication. Pharmaceutical compositions/ and combinations containing one or more substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes and a pharmaceutically acceptable carrier are also provided by this disclosure. Methods for treating viral infections, including Hepatitis C viral infections are provided by the disclosure. 本公开内容提供了可用作抗病毒剂的式(I)D?M?D(式I)的经取代的脂肪芬、环芬、异芬、杂芬、杂?异芬以及金属茂。在本文公开的某些实施方案中，M是基团?P?A?P?，其中A是式(I)。本文公开的某些经取代的脂肪芬、环芬、异芬、杂芬、杂?异芬以及金属茂是强效和/或选择性的病毒复制(特别是丙型肝炎病毒