Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids
The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of HICl, FOXSl, CREB5, IRF7, POU2F2, STAT4, TCF4, and/or an agent that enhances the activity of at least one gene selected from the group co...
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| creator | DARZACQ XAVIER DUGAST-DARZACQ CLAIRE NOIZET MAITE |
| description | The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of HICl, FOXSl, CREB5, IRF7, POU2F2, STAT4, TCF4, and/or an agent that enhances the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2.
本发明涉及用于预防和/或治疗纤维化、增生性疤痕或疤痕疙瘩的治疗性化合物，包含：-抑制至少个选自HIC1、FOXS1、CREB5、IRF7、POU2F2、STAT4、TCF4,优选TCF4、FOXS1、STAT4的基因的活性的试剂，和/或-增强至少个选自MAF、MEOX2、SIX2的基因的活性的试剂。 |
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本发明涉及用于预防和/或治疗纤维化、增生性疤痕或疤痕疙瘩的治疗性化合物，包含：-抑制至少个选自HIC1、FOXS1、CREB5、IRF7、POU2F2、STAT4、TCF4,优选TCF4、FOXS1、STAT4的基因的活性的试剂，和/或-增强至少个选自MAF、MEOX2、SIX2的基因的活性的试剂。</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160720&DB=EPODOC&CC=CN&NR=105793279A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160720&DB=EPODOC&CC=CN&NR=105793279A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DARZACQ XAVIER</creatorcontrib><creatorcontrib>DUGAST-DARZACQ CLAIRE</creatorcontrib><creatorcontrib>NOIZET MAITE</creatorcontrib><title>Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids</title><description>The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of HICl, FOXSl, CREB5, IRF7, POU2F2, STAT4, TCF4, and/or an agent that enhances the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2.
本发明涉及用于预防和/或治疗纤维化、增生性疤痕或疤痕疙瘩的治疗性化合物，包含：-抑制至少个选自HIC1、FOXS1、CREB5、IRF7、POU2F2、STAT4、TCF4,优选TCF4、FOXS1、STAT4的基因的活性的试剂，和/或-增强至少个选自MAF、MEOX2、SIX2的基因的活性的试剂。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNissKwjAQAHvxIOo_rHfFR5HSoxTFi5681zXdmGDMht0o-PdW8AM8zTDMsLgcOZB5BhTIKDfKCpZ7dwRJ6EUxe46AsVt8qxDmR9-ALVh_FVavM3DvRJKFk_MG1KAo9POdAvtOx8XAYlCa_DgqpvvduTnMKXFLmtBQpNw2p9VyU9Xluqq35T_PB_9qPc8</recordid><startdate>20160720</startdate><enddate>20160720</enddate><creator>DARZACQ XAVIER</creator><creator>DUGAST-DARZACQ CLAIRE</creator><creator>NOIZET MAITE</creator><scope>EVB</scope></search><sort><creationdate>20160720</creationdate><title>Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids</title><author>DARZACQ XAVIER ; DUGAST-DARZACQ CLAIRE ; NOIZET MAITE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN105793279A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2016</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DARZACQ XAVIER</creatorcontrib><creatorcontrib>DUGAST-DARZACQ CLAIRE</creatorcontrib><creatorcontrib>NOIZET MAITE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DARZACQ XAVIER</au><au>DUGAST-DARZACQ CLAIRE</au><au>NOIZET MAITE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids</title><date>2016-07-20</date><risdate>2016</risdate><abstract>The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of HICl, FOXSl, CREB5, IRF7, POU2F2, STAT4, TCF4, and/or an agent that enhances the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2.
本发明涉及用于预防和/或治疗纤维化、增生性疤痕或疤痕疙瘩的治疗性化合物，包含：-抑制至少个选自HIC1、FOXS1、CREB5、IRF7、POU2F2、STAT4、TCF4,优选TCF4、FOXS1、STAT4的基因的活性的试剂，和/或-增强至少个选自MAF、MEOX2、SIX2的基因的活性的试剂。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids |
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