N-methoxyl formamide-orientated method for synthesizing ferrocene and pyridone derivative
The invention discloses an N-methoxyl formamide-orientated method for synthesizing a ferrocene and pyridone derivative. According to the method, under the conditions that palladium acetate is taken as a catalyst, copper acetate is taken as a catalyst promoter and quaternary ammonium salt and alkali...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses an N-methoxyl formamide-orientated method for synthesizing a ferrocene and pyridone derivative. According to the method, under the conditions that palladium acetate is taken as a catalyst, copper acetate is taken as a catalyst promoter and quaternary ammonium salt and alkali are taken as additives, an N-methoxyl ferrocene and [c] pyridine-2(1H)-ketone derivative is obtained by carrying out a cyclization reaction on N-methoxyl ferrocene formamide and alkyne. The method adopts an N-methoxyl formamide-orientated carbon-hydrogen bond and nitrogen-hydrogen bond double-activation reaction to synthesize the N-methoxyl ferrocene and [c] pyridine-2(1H)-ketone derivative in one step. The organometallic condensed heterocyclic compounds are unique in structure, thus being hard to prepare by a conventional method; the method provided by the invention has the characteristics of being easy in obtaining of raw materials and mild in reaction conditions, not needing the protection of inert gas, being hi |
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