Japanese encephalitis (JE) vaccine composition and preparing method thereof

The invention provides Japanese encephalitis (JE) vaccine composition. The JE vaccine composition comprises a JE virus antigen of immunization effective quantity and water based vaccine adjuvant. The invention further provides a preparing method and application of the JE vaccine composition. The vac...

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Hauptverfasser:	MA XIAOPING, WEN YIPING, WU RUI, WEN XINTIAN, CAO SANJIE, WANG QIAO, YAN QIGUI, CHAI CHUNXIA, ZHAO QIN, HUANG XIAOBO, FENG YAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides Japanese encephalitis (JE) vaccine composition. The JE vaccine composition comprises a JE virus antigen of immunization effective quantity and water based vaccine adjuvant. The invention further provides a preparing method and application of the JE vaccine composition. The vaccine composition has good immunogenicity and immunizing protection. The immune effect of the JE vaccine composition is remarkably superior to that of single pig JE live vaccine and other live vaccine diluted by immunologic adjuvant. The clinical application prospects are good. 本发明提供了种乙型脑炎疫苗组合物，它含有致免疫有效量的乙型脑炎病毒抗原和水性疫苗佐剂。本发明还提供了所述疫苗组合物的制备方法和用途。本发明疫苗组合物具有良好的免疫原性和免疫保护性，免疫效果显著优于单用猪乙型脑炎活疫苗和其它免疫佐剂稀释的活疫苗，临床应用前景良好。