Preparation method of weak acid cation exchange stationary phase
The invention discloses a preparation method of a weak acid cation chromatographic stationary phase with highly cross-linked glycidyl methacrylate-divinyl benzene microspheres as the matrix. The preparation method comprises the following steps: monodispersed linear polystyrene seed microspheres are...
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| creator | ZHU YAN LIU JUNWEI ZHONG NAIFEI |
| description | The invention discloses a preparation method of a weak acid cation chromatographic stationary phase with highly cross-linked glycidyl methacrylate-divinyl benzene microspheres as the matrix. The preparation method comprises the following steps: monodispersed linear polystyrene seed microspheres are prepared by a dispersion polymerization method; highly cross-linked glycidyl methacrylate-divinyl benzene copolymer microspheres are prepared by a two-step seed swelling method; and by using succinic anhydride, phthalic anhydride, maleic anhydride and maleic acid as reaction materials, the weak acid cation chromatographic stationary phase is prepared.
本发明公开了一种以高交联甲基丙烯酸缩水甘油酯-二乙烯基苯微球为基质的弱酸阳离子色谱固定相的制备方法，采用分散聚合法制备单分散的线性聚苯乙烯种子微球；采用两步种子溶胀法，制备高交联甲基丙烯酸缩水甘油酯-二乙烯基苯共聚微球；以丁二酸酐，邻苯二甲酸酐，马来酸酐和马来酸为反应原料，制备了一种弱酸型阳离子色谱固定相。 |
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本发明公开了一种以高交联甲基丙烯酸缩水甘油酯-二乙烯基苯微球为基质的弱酸阳离子色谱固定相的制备方法，采用分散聚合法制备单分散的线性聚苯乙烯种子微球；采用两步种子溶胀法，制备高交联甲基丙烯酸缩水甘油酯-二乙烯基苯共聚微球；以丁二酸酐，邻苯二甲酸酐，马来酸酐和马来酸为反应原料，制备了一种弱酸型阳离子色谱固定相。</description><language>chi ; eng</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; SEPARATION ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160615&DB=EPODOC&CC=CN&NR=105664886A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160615&DB=EPODOC&CC=CN&NR=105664886A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHU YAN</creatorcontrib><creatorcontrib>LIU JUNWEI</creatorcontrib><creatorcontrib>ZHONG NAIFEI</creatorcontrib><title>Preparation method of weak acid cation exchange stationary phase</title><description>The invention discloses a preparation method of a weak acid cation chromatographic stationary phase with highly cross-linked glycidyl methacrylate-divinyl benzene microspheres as the matrix. The preparation method comprises the following steps: monodispersed linear polystyrene seed microspheres are prepared by a dispersion polymerization method; highly cross-linked glycidyl methacrylate-divinyl benzene copolymer microspheres are prepared by a two-step seed swelling method; and by using succinic anhydride, phthalic anhydride, maleic anhydride and maleic acid as reaction materials, the weak acid cation chromatographic stationary phase is prepared.
本发明公开了一种以高交联甲基丙烯酸缩水甘油酯-二乙烯基苯微球为基质的弱酸阳离子色谱固定相的制备方法，采用分散聚合法制备单分散的线性聚苯乙烯种子微球；采用两步种子溶胀法，制备高交联甲基丙烯酸缩水甘油酯-二乙烯基苯共聚微球；以丁二酸酐，邻苯二甲酸酐，马来酸酐和马来酸为反应原料，制备了一种弱酸型阳离子色谱固定相。</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>SEPARATION</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAIKEotSCxKLMnMz1PITS3JyE9RyE9TKE9NzFZITM5MUUiGSKVWJGck5qWnKhSXgAUSiyoVCjISi1N5GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakm8s5-hgamZmYmFhZmjMTFqANHVMXM</recordid><startdate>20160615</startdate><enddate>20160615</enddate><creator>ZHU YAN</creator><creator>LIU JUNWEI</creator><creator>ZHONG NAIFEI</creator><scope>EVB</scope></search><sort><creationdate>20160615</creationdate><title>Preparation method of weak acid cation exchange stationary phase</title><author>ZHU YAN ; LIU JUNWEI ; ZHONG NAIFEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN105664886A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2016</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>SEPARATION</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHU YAN</creatorcontrib><creatorcontrib>LIU JUNWEI</creatorcontrib><creatorcontrib>ZHONG NAIFEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHU YAN</au><au>LIU JUNWEI</au><au>ZHONG NAIFEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of weak acid cation exchange stationary phase</title><date>2016-06-15</date><risdate>2016</risdate><abstract>The invention discloses a preparation method of a weak acid cation chromatographic stationary phase with highly cross-linked glycidyl methacrylate-divinyl benzene microspheres as the matrix. The preparation method comprises the following steps: monodispersed linear polystyrene seed microspheres are prepared by a dispersion polymerization method; highly cross-linked glycidyl methacrylate-divinyl benzene copolymer microspheres are prepared by a two-step seed swelling method; and by using succinic anhydride, phthalic anhydride, maleic anhydride and maleic acid as reaction materials, the weak acid cation chromatographic stationary phase is prepared.
本发明公开了一种以高交联甲基丙烯酸缩水甘油酯-二乙烯基苯微球为基质的弱酸阳离子色谱固定相的制备方法，采用分散聚合法制备单分散的线性聚苯乙烯种子微球；采用两步种子溶胀法，制备高交联甲基丙烯酸缩水甘油酯-二乙烯基苯共聚微球；以丁二酸酐，邻苯二甲酸酐，马来酸酐和马来酸为反应原料，制备了一种弱酸型阳离子色谱固定相。</abstract><oa>free_for_read</oa></addata></record> |
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| title | Preparation method of weak acid cation exchange stationary phase |
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