Method for preparing three-dimensional interconnected blood vessel-liked structure network scaffold by roller type collection

The invention discloses a method for preparing a three-dimensional interconnected blood vessel-liked structure network scaffold by roller type collection. The method is based on hot-melt extrusion of water-soluble materials, the roller type collection mode is used for forming a prefabricated three-d...

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Bibliographische Detailangaben
Hauptverfasser:	LIU YUANYUAN, HU QINGXI, LI YU, LI SHUAI, SUN YUANSHAO, LIU CHANGE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ADDITIVE MANUFACTURING TECHNOLOGY ADDITIVE MANUFACTURING, i.e. MANUFACTURING OFTHREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVEAGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING,STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS PERFORMING OPERATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP TRANSPORTING
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Beschreibung
Zusammenfassung:	The invention discloses a method for preparing a three-dimensional interconnected blood vessel-liked structure network scaffold by roller type collection. The method is based on hot-melt extrusion of water-soluble materials, the roller type collection mode is used for forming a prefabricated three-dimensional entity network, a hydrogel material is used for embedding, after moulding, the material is placed in water, the three-dimensional entity network is removed, and the three-dimensional interconnected blood vessel-liked structure network is formed in the hydrogel. A three-dimensional idea for traditional connection between layers is broken through, the characteristics of the cylindrical roller is used, the cylindrical surface is used for receiving the water-soluble material, and the entity network with the three-dimensional structure which is formed after extrusion is constructed. 本发明公开了滚筒式收集制备三维贯通类血管结构网络支架的方法。该方法在热熔挤出水溶性材料的基础上，采用滚筒收集的方式来形成预制的三维实体网络，再用水凝胶材料进行包埋，成型完毕后放入水中，去除三维实体网络，在水凝胶内部形成三维贯通的类血管结构网络。本发明打破了