Mass spectrometric identification and/or quantitation of catecholamines using aminopyrazoles

A method is described for mass spectrometric analysis, detection and quantification of catecholamines. The methods can comprise reacting the catecholamines with a 4- aminoantippyrine reagent and detecting and/or quantifying the adduct produced by the reaction. The methods can also allow for multiple...

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Hauptverfasser: PURKAYASTHA SUBHASISH, DEY SUBHAKAR N
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:A method is described for mass spectrometric analysis, detection and quantification of catecholamines. The methods can comprise reacting the catecholamines with a 4- aminoantippyrine reagent and detecting and/or quantifying the adduct produced by the reaction. The methods can also allow for multiplexing. Compounds formed by the reactions are also provided. 本发明描述种用于质谱分析、检测和定量儿茶酚胺的方法。所述方法可包含使所述儿茶酚胺与4-氨基安替比林试剂反应并且检测和/或定量所述反应产生的加合物。所述方法也可以允许同时进行多次。还提供所述反应形成的化合物。