Dynamic assay selection and sample preparation apparatus and methods and machine-readable mediums thereof

Automated methods of preparing patient samples for assays are disclosed. The methods include performing sample processing of multiple patient samples in multiple extraction wells of an extraction plate to prepare multiple eluded samples in at least some of the multiple extraction wells, and transferring, based upon an electronic plate map including multiple assay regions, one of the multiple eluded samples from a single extraction well of the multiple extraction wells into multiple test wells of the test plate, wherein each of the multiple test wells of the test plate are configured to carry out a different assay and receives a different master mix for a different assay type. Sample preparation apparatus configured to carry out the methods are described, as are other aspects