A tadalafil solid dispersoid and a preparing method of a medicine preparation of the tadalafil solid dispersoid

A tadalafil solid dispersoid and a preparing method of a medicine preparation of the tadalafil solid dispersoid

The invention discloses a preparing method of a tadalafil solid dispersoid. An ethanol-acetone mixed solvent is adopted. The ratio of the ethanol to the acetone is 7:3-3:7(v/v), preferentially 6:4-4:6(v/v). The using amount of the solvent in a preparation process can be greatly reduced. The inventio...

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Bibliographische Detailangaben
Hauptverfasser: HU LIBIN, CHEN HAO, LAN FEIFEI, CAO YU, LI CHUNYAN, TU HOUWEI
Format: Patent
Sprache:chi ; eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention discloses a preparing method of a tadalafil solid dispersoid. An ethanol-acetone mixed solvent is adopted. The ratio of the ethanol to the acetone is 7:3-3:7(v/v), preferentially 6:4-4:6(v/v). The using amount of the solvent in a preparation process can be greatly reduced. The invention further discloses a tadalafil tablet comprising the tadalafil solid dispersoid and a preparing method thereof.