Preparation and application of nitrite scavenging agent

The invention relates to preparation and an application of a phenylpropyl dibenzyl butyrolactone composition. A compound having a phenylpropyl dibenzyl butyrolactone parent nucleus serves as an initial compound, and is subjected to structure modification research to obtain a compound as shown in a s...

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Bibliographische Detailangaben
Hauptverfasser: HAN MEI, CAI ENBO, TU SHUMEI, JIAN LIANGQIN, ZHANG WEIYUAN, SONG XINGZHUO, LI WEI, ZHANG YU, ZHENG XIAOMAN, YIN YU, LI XINDIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to preparation and an application of a phenylpropyl dibenzyl butyrolactone composition. A compound having a phenylpropyl dibenzyl butyrolactone parent nucleus serves as an initial compound, and is subjected to structure modification research to obtain a compound as shown in a structural general formula I. The compound has the activity of cleaning nitrite, can be used for preventing and treating cancers, and has a wide application prospect. In the general formula I, R is Boc-L-Gly, Boc-L-Ala, Boc-L-Val, Boc-L-Leu and Boc-L-Ile amino acid side chains.