Electrowetting based conformal light sensing integrated digital microfluidic chip

The present invention discloses a conformal light-sensing structure integrated digital microfluidic chip which can monitor a chemical reaction between droplets carrying different components in a digital microfluidic chip in real-time, in the detection application field of digital microfluidic bioche...

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Bibliographische Detailangaben
Hauptverfasser: LIU HAITAO, JIN HONGLI, CHEN LUOYANG, LIU JIANSHENG, ZHENG ZHENG, CHENG JIANGTAO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention discloses a conformal light-sensing structure integrated digital microfluidic chip which can monitor a chemical reaction between droplets carrying different components in a digital microfluidic chip in real-time, in the detection application field of digital microfluidic biochemical detection on consumption for a low level sample. According to the chip disclosed by the present invention, on the basis of no change of a current structure and property of electrowetting, a subwavelength scale optical sensing structure is embedded between electrowetting adjacent electrode gaps; a co-planar conformal structure with a hydrophobic layer of the electrowetting structure is kept in structure; by detecting a change of a light-sensing structure light field which is caused by a small change in a refractive index occurring during a process of the droplets reaction, determination for composition and location of a microdroplet is realized. Compared with light sensing composed of a conventional capacitor,