Niclosamide ethanolamine self-emulsifying micro-emulsion and preparation method thereof

The invention relates to the technical field of pharmacy and particularly relates to a pesticide niclosamide ethanolamine self-emulsifying micro-emulsion for killing oncomelania and a preparation method thereof. The niclosamide ethanolamine self-emulsifying micro-emulsion provided by the invention i...

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Bibliographische Detailangaben
Hauptverfasser: ZHONG ZHIHONG, CHEN HONG, ZHANG MINGHUI, XU HONG, HAO SHIXUAN, YI CHENGXUE, CAO WENTING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of pharmacy and particularly relates to a pesticide niclosamide ethanolamine self-emulsifying micro-emulsion for killing oncomelania and a preparation method thereof. The niclosamide ethanolamine self-emulsifying micro-emulsion provided by the invention is prepared from niclosamide ethanolamine, an oil phase, an emulsifying agent and an auxiliary emulsifying agent, wherein the mass ratio of all the components is that the niclosamide ethanolamine to the oil phase to the emulsifying agent to the auxiliary emulsifying agent is 1 to (1-15) to (5-30) to (5-20). The niclosamide ethanolamine self-emulsifying micro-emulsion has the following beneficial effects: 1, the dissolving rate of the pesticide is greatly improved and the dispersity of the pesticide in a water body system is improved; 2, the product does not contain aromatic series organic solvents, and organic solvents which seriously pollute the environments, such as N-methyl pyrrolidone, dimethylformamide and cycl