Long QT syndrome (LQTs)-related miRNA (microribonucleic acid) and application thereof

The invention discloses a molecular marker capable of prognosing long QT syndrome (LQTs) attack risks and diagnosing the LQTs, namely miRNA (microribonucleic acid)-3619, and an application of antisense oligonucleotides AMO-3619 of miRNA-3619 in preparation of medicines for treating the LQTs, mainly...

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Bibliographische Detailangaben
Hauptverfasser:	FANG PEILIANG, YANG XI, GUO JIAN, ZHOU JIANQING, MAO HAIYAN, LIAN JIANGFANG, ZHENG MEIXIA, ZHUANG KAILI, HUANG XIAOYAN, BA YANNA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a molecular marker capable of prognosing long QT syndrome (LQTs) attack risks and diagnosing the LQTs, namely miRNA (microribonucleic acid)-3619, and an application of antisense oligonucleotides AMO-3619 of miRNA-3619 in preparation of medicines for treating the LQTs, mainly an application of the medicines in promotion of human ether-a-Go-Go related gene (hERG) functions. The molecular marker is characterized in that the medicine composition contains AMO-3619.