Preparation of isothiocyanate compounds

Disclosed is a sustained-release preparation or capsule of isothiocyanate compounds or derivatives thereof, the sustained-release preparation containing (a) a therapeutically effective amount of isothiocyanate compounds or derivatives thereof; (b) a pharmaceutically acceptable carrier, and the capsule containing a capsule shell and a pharmaceutical composition consisting of components (a) and (b) inside the capsule shell. The sustained-release preparation is stable and has a good compatibility and sustained-release effect; the capsule significantly improves the stability of the drug, and masks the smell of the isothiocyanate compounds and reduces irritation.