Pesticide composition as well as preparation method and application thereof

The invention discloses a pesticide composition as well as a preparation method and application thereof. The pesticide composition comprises the following particular constituents in percentage by weight: 1%-90% of effective constituents and 10%-99% of a pesticide carrier, wherein the effective constituents are JS399-19 and fluensulfone, and the weight ratio of JS399-19 to fluensulfone is (1-60):(60-1). The synergistic effect of mixing of JS399-19 and fluensulfone is utilized for making up the own insufficiencies of a single-dose pesticide, the drug resistance of plant diseases and insect pests is avoided, the medicament application effect is improved, the bactericidal spectrum is enlarged, the toxicity is lower, and the economic benefits and environment-friendly benefits are obvious. Lots of experiments prove that after combination of JS399-19 and fluensulfone according to the weight ratio, the control effects on all of the rice bakanae disease, the aphelenchoides besseyi, the vegetable fusarium wilt, the nematodosis and the like are remarkable.