Phosphorus-containing pyridine[2,3-d]pyrimidine-7-ketone compound or pharmaceutically acceptable salt, pharmaceutical composition and application thereof

Phosphorus-containing pyridine[2,3-d]pyrimidine-7-ketone compound or pharmaceutically acceptable salt, pharmaceutical composition and application thereof

The invention provides a phosphorus-containing pyridine[2,3-d]pyrimidine-7-ketone compound as shown in the formula (I) or its pharmaceutically acceptable salt, and also discloses a preparation method of the compound, a pharmaceutical composition containing the phosphorus-containing pyridine[2,3-d]py...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: LYU HUIMIN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides a phosphorus-containing pyridine[2,3-d]pyrimidine-7-ketone compound as shown in the formula (I) or its pharmaceutically acceptable salt, and also discloses a preparation method of the compound, a pharmaceutical composition containing the phosphorus-containing pyridine[2,3-d]pyrimidine-7-ketone compound and an application thereof. The compound is a protein kinase (such as PI3K) inhibitor and can be used in treating diseases caused by abnormal protein kinase activities, such as tumour, etc.