Doxercalciferol enteric-coated tablet and preparation method thereof

The invention relates to a doxercalciferol enteric-coated tablet and a preparation method thereof. The enteric-coated tablet consists of a tablet core and an enteric coating, wherein the enteric coating layer contains 5-15% of enteric materials by weight percent, and the tablet core is prepared from...

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1. Verfasser: GAO JINGXUAN
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to a doxercalciferol enteric-coated tablet and a preparation method thereof. The enteric-coated tablet consists of a tablet core and an enteric coating, wherein the enteric coating layer contains 5-15% of enteric materials by weight percent, and the tablet core is prepared from the following components by weight percent: doxercalciferol, PEG 6000, filling agent, disintegrating agent, antioxygen and an appropriate of adhesive. According to the doxercalciferol enteric-coated tablet and the preparation method thereof, the content of doxercalciferol is improved, the stability of doxercalciferol resisting to light and air is improved, the dissolution speed is improved, and the bioavailability of the doxercalciferol is also remarkably improved. Compared with the prior art, the doxercalciferol enteric-coated tablet has the characteristics of simple production process, low cost, high safety, convenience in use and the like.