D-tartaric acid monoester monoamide compound
The invention relates to a D-tartaric acid monoester monoamide compound, capable of serving as a ligand to catalytically synthesize R type chirality proton pump inhibitors such as Dexlansoprazole. A synthesis method comprises the steps of dissolving a compound II and the D-tartaric acid monoester mo...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The invention relates to a D-tartaric acid monoester monoamide compound, capable of serving as a ligand to catalytically synthesize R type chirality proton pump inhibitors such as Dexlansoprazole. A synthesis method comprises the steps of dissolving a compound II and the D-tartaric acid monoester monoamide compound into an organic solvent, and heating to react, thus obtaining the R type chirality proton pump inhibitors such as the Dexlansoprazole. The method has higher yield and e.e value. |
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