Fusion protein and its preparation method and use

The invention provides a fusion protein. Through fusion expression of HAS and IL21, the fusion protein is prepared. The fusion protein has IL21 activity, substantially prolongs an IL21 half life and greatly improves stability. The invention also provides a nucleic acid sequence for coding the fusion...

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Bibliographische Detailangaben
Hauptverfasser:	FU MEILAN, KONG CHAO, WANG HAIMING, XU FANHONG
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a fusion protein. Through fusion expression of HAS and IL21, the fusion protein is prepared. The fusion protein has IL21 activity, substantially prolongs an IL21 half life and greatly improves stability. The invention also provides a nucleic acid sequence for coding the fusion protein and a preparation method of the fusion protein.