Micro-nano structure end surface optical fiber embedded Raman detection microfluidic chip

The invention relates to a micro-nano structure end surface optical fiber embedded Raman detection microfluidic chip. The optical fiber with micro-nano structure end surface is embedded as collecting optical fiber into a microfluidic chip, exciting optical fiber and collecting optical fiber are coupled according to certain angle and position, laser-induced enrichment of gold nanoparticles is utilized to enhance Raman scattering so as to realize Raman detection and analysis on a liquid sample. When detection is carried out on a sample solution based on gold nanoparticle enhanced Raman scattering, the sample solution is injected through a sample filling port, so that the end faces of the exciting optical fiber and collecting optical fiber in a detection tank completely dip into the sample solution, the laser emerging from the exciting optical fiber irradiate the sample solution continuously and shines the microstructure end face of the collecting optical fiber. Under the action of photo-induced enrichment of gold nanoparticles, the gold nanoparticles are enriched at the end face of the collecting optical fiber, the micro-nano structure end surface of the collecting optical fiber can significantly enhance the enrichment effect of gold nanoparticles, and can constantly reinforce the Raman scattering detection signal of the sample. The microfluidic chip provided by the invention realizes the whole process based on gold nanoparticle enhanced Raman detection, and provides a solution for miniaturization and portability of Raman detection.