Preparation method of hydrogel for cartilage repair and with tissue inductivity

The invention discloses a preparation method of hydrogel for cartilage repair and with tissue inductivity. The preparation method comprises the following main steps: A, polysaccharide or protein double bonding, B, hydrogel preparation, and C, adsorption of growth factors. According to the preparation method, double bonded natural polysaccharide/protein and methacrylamide dopamine which are completely degradable are used as the main components, and hydrogel adopting a double network structure can be formed through free radical polymerization of two materials of double bonded polysaccharide/protein and methacrylamide dopamine. Then hydrogel adsorbs biological activity growth factors through the dehydration and reswelling functions, and the growth factors are fixed into hydrogel throguh the dopamine component. The hydrogel obtained according to the preparation method is excellent in biological degradability and cell/tissue affinity, high in activity of the loaded growth factors and good in slow release performance, and can better induce cartilage regeneration and promote cartilage repair.