Curcumin derivative fluorescent molecular probe and application thereof

The invention discloses a new crcumin derivative fluorescent molecular probe. The probe is with a general formula in the following structure as shown in the description, wherein R can be hydrogen, fluorine, chlorine, bromine, iodine, methoxyl, ethoxyl, nitroglycerine, or an alkyl chain with 1-3 carb...

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Bibliographische Detailangaben
Hauptverfasser:	XIANG DECHENG, MENG QINGHUA
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ADHESIVES CHEMISTRY DYES INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE MEASURING METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS NATURAL RESINS ORGANIC CHEMISTRY PAINTS PHYSICS POLISHES TESTING
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Beschreibung
Zusammenfassung:	The invention discloses a new crcumin derivative fluorescent molecular probe. The probe is with a general formula in the following structure as shown in the description, wherein R can be hydrogen, fluorine, chlorine, bromine, iodine, methoxyl, ethoxyl, nitroglycerine, or an alkyl chain with 1-3 carbon atoms. The invention also discloses an application of the new crcumin derivative fluorescent molecular probe in the field of pH-responsive fluorescence detection, wherein a fluorescence response region is a acidic-to-neutral pH condition, and a range of a pH value is 2-8. Compared with an existing traditional curcumin molecular probe, the fluorescent molecular probe provided by the invention is free of effects of a intramolecular hydrogen bond and metal chelating effects, and fluorescence enhancement is improved exponentially.