Copper-based human albumin nano-composite with near infrared thermal effect as well as preparation method and application of copper-based human albumin nano-composite

The invention discloses a copper-based human albumin nano-composite with a near infrared thermal effect as well as a preparation method and an application of the copper-based human albumin nano-composite. Growth of an inorganic copper-based nano-composite is induced by controlling the protein concen...

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Hauptverfasser: GUO ZHENGQING, YANG HONG, JI SHUANGSHUANG, ZOU YELIN, YANG TAO, CHEN HUABING, DENG YIBIN, KE HENGTE, WANG QIAOLI, HE HUI, WANG YONG
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a copper-based human albumin nano-composite with a near infrared thermal effect as well as a preparation method and an application of the copper-based human albumin nano-composite. Growth of an inorganic copper-based nano-composite is induced by controlling the protein concentration, the concentration of a copper salt, the pH of a reaction solution, the reaction time and the reaction temperature; and the copper-based nano structure of a copper sulphate or copper selenide-coated nano composite employing human albumin as a skeleton is synthesized. The copper-based human albumin nano-composite with the near infrared thermal effect has the characteristics of good dispersity, good light stability, high photothermal conversion efficiency, good in-vivo tumor targeting property and the like, and can be applied to photothermal therapy; and efficient heat removal of tumors is realized.