Preparation method of choline glycerophosphate crystal

The invention discloses a preparation method of a choline glycerophosphate crystal. The preparation method comprises steps as follows: (1), choline glycerophosphate and alcohol are mixed, and a mixture M1 is prepared; (2), the mixture M1 and sulfate are mixed and cooled for primary filtering, a filtrate is taken, and a mixture M2 is obtained; (3), the mixture M2 is subjected to primary concentration, and a mixture M3 is prepared; (4), the mixture M3 and an organic solvent are mixed and subjected to secondary concentration, and a mixture M4 is prepared; (5), ethyl acetate and the mixture M4 are mixed and crystalized for secondary filtering, and a crystal M5 is obtained; (6), the crystal M5 is subjected to postprocessing and the choline glycerophosphate crystal is obtained. The choline glycerophosphate crystal prepared with the method has low water absorption in air, high purity and higher healthcare property and medicinal value.