Drug loaded composite bone restoration material and preparation method thereof

The invention discloses a drug loaded composite bone restoration material and a preparation method thereof. The drug loaded composite bone restoration material is prepared through compounding an inorganic nano-material hydroxyapatite (n-HA), a synthetic polymer material polyamide (PA) and a natural...

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Bibliographische Detailangaben
Hauptverfasser: ZHOU LI, LIU BO, WU FENGQUN, LYU WEIZHONG, HU HUIYUAN, YANG FEI, LUO ZHONGKUAN, WU YIGUANG
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a drug loaded composite bone restoration material and a preparation method thereof. The drug loaded composite bone restoration material is prepared through compounding an inorganic nano-material hydroxyapatite (n-HA), a synthetic polymer material polyamide (PA) and a natural polymer chitosan (CS), and loading an antibiotic drug erythromycin (EM). The n-HA is a main component of bones, PA has a human bone-like collagen structure, CS has a bacteriostasis effect and a wound healing promoting effect and has a degradation speed matching with the bone growth speed, and the loaded EM has infection prevention and treatment effects, so the bone restoration material is a novel bone tissue material with anti-infection ability and efficient bone formation activity, can restore bone defects and treat infection or tumors, and can truly realize bone defect restoration treatment.