Recombinant human interferon alpha 2b gel and preparation method thereof

The invention discloses a recombinant human interferon alpha 2b gel. A preparation method of the recombinant human interferon alpha 2b gel comprises the following steps: (a) putting Carbomer into water for injection for swelling over night; (b) weighing and mixing propylene glycol, Tween 80, EDTA (ethylene diamine tetraacetic acid), glycerol and ethylparaben, adding water for injection, of which the weight is 1-2 times of the weight of the mixture, heating and stirring under the water bath condition of 70-80 DEG C until ethylparaben is completely dissolved, adding the dissolved solution into the swollen Carbomer matrix solution, uniformly mixing, adding triethanolamine to adjust the pH value to be 5.0-7.5, and carrying out moist heat sterillization for 0.5-2 hours to obtain a Carbomer matrix for later use; (c) dissolving pharmaceutical gelatin by a pH buffer solution, carrying out sterilization treatment under pressurized and heated conditions, cooling to the temperature lower than 25 DEG C, then adding recombinant human interferon alpha 2b for dissolving, and stirring uniformly for later use; (d) adding the recombinant human interferon alpha 2b gelatin solution into the Carbomer matrix, stirring uniformly, and then putting the mixture into a hose or a gynecological syringe, thereby obtaining a finished product. The recombinant human interferon alpha 2b gel prepared by the method disclosed by the invention has the advantages of low cost and good stability.