Preparation and application of magnetic graphene oxide compound
The invention relates to preparation and application of a reusable drug carrier with magnetic targeting drug delivery, namely a magnetic graphene oxide compound. The preparation of the magnetic graphene oxide compound comprises the following steps: (1) taking a graphite powder, adding a concentrated...
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| creator | LI LIANGCHAO ZHANG JINMIN QUAN WEILEI FENG JIANTAO SHEN JUNHAI |
| description | The invention relates to preparation and application of a reusable drug carrier with magnetic targeting drug delivery, namely a magnetic graphene oxide compound. The preparation of the magnetic graphene oxide compound comprises the following steps: (1) taking a graphite powder, adding a concentrated H2SO4 solution with NaNO3 dissolved therein, stirring, adding KMnO4, reacting, adding distilled water for dilution, keeping warm, cooling to room temperature, adding H2O2 to react, conducting suction filtration, washing respectively with diluted hydrochloric acid and distilled water, carrying out vacuum drying to obtain graphite oxide; dispersing graphite oxide in deionized water, and carrying out ultrasonic exfoliation at room temperature to obtain a GO suspension; (2) respectively weighing ferrous salt and ferric salt and dissolving in deionized water to obtain a solution A; and (3) taking a GO suspension, adding distilled water for dilution, adjusting to acid, dropwise adding the solution A obtained in the step (2) so as to obtain a mixed solution B, carrying out constant temperature curing on the mixed solution B, adjusting to alkaline, ageing for several hours, carrying out magnetic separation to obtain a solid crude product, washing the solid crude product to neutral, and carrying out vacuum drying to obtain the product. |
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The preparation of the magnetic graphene oxide compound comprises the following steps: (1) taking a graphite powder, adding a concentrated H2SO4 solution with NaNO3 dissolved therein, stirring, adding KMnO4, reacting, adding distilled water for dilution, keeping warm, cooling to room temperature, adding H2O2 to react, conducting suction filtration, washing respectively with diluted hydrochloric acid and distilled water, carrying out vacuum drying to obtain graphite oxide; dispersing graphite oxide in deionized water, and carrying out ultrasonic exfoliation at room temperature to obtain a GO suspension; (2) respectively weighing ferrous salt and ferric salt and dissolving in deionized water to obtain a solution A; and (3) taking a GO suspension, adding distilled water for dilution, adjusting to acid, dropwise adding the solution A obtained in the step (2) so as to obtain a mixed solution B, carrying out constant temperature curing on the mixed solution B, adjusting to alkaline, ageing for several hours, carrying out magnetic separation to obtain a solid crude product, washing the solid crude product to neutral, and carrying out vacuum drying to obtain the product.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Preparation and application of magnetic graphene oxide compound |
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