Pulsatilla chinensis extract and application thereof to preparation of drugs for preventing and treating pulmonary fibrosis

The invention discloses a pulsatilla chinensis extract and application thereof to the preparation of drugs for preventing and treating pulmonary fibrosis. The pulsatilla chinensis extract uses pulsatilla chinensis as a raw material and is prepared through the following steps: firstly, adding ethanol for extraction, concentrating the obtained extracting solution until an extractum is obtained, and then extracting, concentrating and drying the extractum sequentially to obtain pulsatilla chinensis total saponins; adding distilled water into the residue after extraction, decocting and extracting, concentrating the extracting solution until an extractum is obtained, and then treating the extractum to obtain pulsatilla chinensis polysaccharide; mixing the pulsatilla chinensis total saponins with the pulsatilla chinensis polysaccharide uniformly to obtain the final pulsatilla chinensis extract. Through experimental verification, the pulsatilla chinensis extract can prevent the formation and development of pulmonary fibrosis by inhibiting the proliferation of lung fibroblast and the transformation of alveolar epithelial cells to mesenchymal cells, so that the pulsatilla chinensis extract achieves new application to the preparation of drugs for preventing and treating pulmonary fibrosis.