Tilmicosin slow release pellet, and preparation method and application thereof

The invention discloses a tilmicosin slow release pellet, and a preparation method and an application thereof. The tilmicosin slow release pellet sequentially comprises a slow release coating layer and a drug-containing pellet core from outside to inside, wherein the weight of the slow release coating layer is 10-100% of the weight of the drug-containing pellet core. The diameter of the tilmicosin slow release pellet is smaller than 2.5mm, and the pellet is a unit preparation, so the pellet has the advantages of large drug load, small local irritation, high bioavailability and stable drug release. The tilmicosin slow release pellet can continuously release the drug within a long time to realize a long-acting effect, and also has the advantages of administration frequency reduction, maintenance of lasting and stable plasma concentration, avoiding of peaks and valleys, improvement of the curative effect, and reduction of the toxic side effects of the drug.