Human recombinant [beta]-interferon fusion protein

Human recombinant [beta]-interferon fusion protein

The invention relates to human recombinant [beta]-interferon fusion protein, which is a fusion protein of human [beta]-interferon and an anti-human serum albumin heavy chain single-domain antibody. The amino acid sequence of the fusion protein is represented as the Seq ID No.1 and the amino acid seq...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FAN MINGJUN, ZHANG JINKUO, LI HUAPING, ZHU MIAOMIAO, QIAN LIUQING
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The invention relates to human recombinant [beta]-interferon fusion protein, which is a fusion protein of human [beta]-interferon and an anti-human serum albumin heavy chain single-domain antibody. The amino acid sequence of the fusion protein is represented as the Seq ID No.1 and the amino acid sequence of the anti-human serum albumin heavy chain single-domain antibody is represented as the Seq ID No.2. In the invention, by means of construction of the fusion expression cloning of the anti-human serum albumin heavy chain single-domain antibody and the [beta]-interferon and introduction into a host cell for expression, a heavy chain single-domain antibody-[beta]-interferon fusion protein having a long acting time is obtained.