Calixpyridine-pyrenetetrasulfonid acid tetrasodium salt supramolecular fluorescence sensor, and its application in ATP hydrolysis reaction

The invention discloses a calixpyridine-pyrenetetrasulfonid acid tetrasodium salt supramolecular fluorescence sensor, and its application in an ATP hydrolysis reaction. The supermolecular fluorescence sensing system is constructed through host-guest inclusion complexation interaction with calixpyrid...

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Hauptverfasser: WANG KUI, DOU HONGXI
Format: Patent
Sprache:eng
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Zusammenfassung:The invention discloses a calixpyridine-pyrenetetrasulfonid acid tetrasodium salt supramolecular fluorescence sensor, and its application in an ATP hydrolysis reaction. The supermolecular fluorescence sensing system is constructed through host-guest inclusion complexation interaction with calixpyridine as a host and pyrenetetrasulfonid acid tetrasodium salt as a guest, the concentration of calixpyridine in the system is 0.004mmol/L, and the concentration of the pyrenetetrasulfonid acid tetrasodium salt in the system is 0.001mmol/L. The supermolecular fluorescence sensor can selectively detect alkaline phosphatase CIAP, and the content of the alkaline phosphatase CIAP in many cancer cells is higher than the expression value of the alkaline phosphatase CIAP in normal cells, so the supermolecular fluorescence sensor has wide potential application values in selective detection of the alkaline phosphatase CIAP in the biological medicine field.