SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS

The present invention relates to novel spiro-quinazolinone derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling.

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Bibliographische Detailangaben
Hauptverfasser: HAXELL THOMAS FRANCIS NELSON, SUTTON AMANDA E, DORSEY JAMES M, FOGLESONG ROBERT JAMES, BRUGGER NADIA, RICHARDSON THOMAS E, HODOUS BRIAN L, POTNICK JUSTIN, JOHNSON THERESA L
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel spiro-quinazolinone derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling.