Ticagrelor solid preparation and preparation method thereof

Ticagrelor solid preparation and preparation method thereof

The invention relates to a ticagrelor solid preparation and a preparation method thereof. The solid preparation contains active pharmaceutical ingredients including ticagrelor and a diluent, wherein the diluent is a combination of mannitol and microcrystalline cellulose; and furthermore, the weight...

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1. Verfasser: FENG SHUIWANG
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator FENG SHUIWANG
description The invention relates to a ticagrelor solid preparation and a preparation method thereof. The solid preparation contains active pharmaceutical ingredients including ticagrelor and a diluent, wherein the diluent is a combination of mannitol and microcrystalline cellulose; and furthermore, the weight proportion of mannitol to microcrystalline cellulose is 0.2:1 to 3:1. The solid preparation provided by the invention is capable of promoting drugs to dissolve out completely while accelerating drugs to dissolve out; therefore, the solid preparation is high in bioavailability and good in storage stability; furthermore, the invention further provides a preparation method of the ticagrelor solid preparation; and the preparation method is simple and feasible and low in production cost and is applied to industrial production.
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The solid preparation provided by the invention is capable of promoting drugs to dissolve out completely while accelerating drugs to dissolve out; therefore, the solid preparation is high in bioavailability and good in storage stability; furthermore, the invention further provides a preparation method of the ticagrelor solid preparation; and the preparation method is simple and feasible and low in production cost and is applied to industrial production.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150930&amp;DB=EPODOC&amp;CC=CN&amp;NR=104940204A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150930&amp;DB=EPODOC&amp;CC=CN&amp;NR=104940204A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FENG SHUIWANG</creatorcontrib><title>Ticagrelor solid preparation and preparation method thereof</title><description>The invention relates to a ticagrelor solid preparation and a preparation method thereof. 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The solid preparation contains active pharmaceutical ingredients including ticagrelor and a diluent, wherein the diluent is a combination of mannitol and microcrystalline cellulose; and furthermore, the weight proportion of mannitol to microcrystalline cellulose is 0.2:1 to 3:1. The solid preparation provided by the invention is capable of promoting drugs to dissolve out completely while accelerating drugs to dissolve out; therefore, the solid preparation is high in bioavailability and good in storage stability; furthermore, the invention further provides a preparation method of the ticagrelor solid preparation; and the preparation method is simple and feasible and low in production cost and is applied to industrial production.</abstract><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Ticagrelor solid preparation and preparation method thereof
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