Synthetic method of 5-chloro-1-indanone

The invention discloses a synthetic method of 5-chloro-1-indanone, and belongs to the field of organic synthesis. 3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150 DEG C. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 DEG C. The synthesis process of 5-chloro-1-indanone provided by the invention is simple and easy for magnification, resolves the technical problems of in the presence of long synthetic route, expensive catalysts or raw materials, harsh reaction conditions and high cost in the current synthetic method; particularly in the environment, compared with the conventional synthetic method of 5-chloro-1-indanone process, the method provided by the invention avoids environmental pollution problem caused by strong acid and treatment of a large amount of wastewater.