Macrocyclic Compounds Useful As Pharmaceuticals

The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	FUJITA MASANORI, CHIBA KENICH, KAWAI TAKATOSHI, GOTO MASAKI, LEMELIN CHARLES-ANDRE, MIZUI YOSHIHARU, SHIROTA HIROSHI, LI XIANG-YI, EGUCHI YOSHIHITO, HARMANGE JEANRISTOPHE, GUSOVSKY FABIAN, YONEDA NAOKI, MURAMOTO KENZO, DU HONG, KAWAKAMI YOSHIYUKI, TANAKA ISAO, BOIVIN ROCH, KUBOI YOSHIKAZU, YAMAMOTO SATOSHI, KOTAKE MAKOTO, WANG JOHN YUAN, JIANG YIMIN, CHOW JESSE, SUKURAI HIDEKI, KIMURA AKIFUMI, SPYVEE MARK, INOUE ATSUSHI, SHEN YONGUN, MATSUSHIMA TOMOHIRO, KAWADA MEGUMI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1 -R11, t, X, Y, Z, and n are as defined herein.