Microorganism producing O-phosphoserine and method of producing L-cysteine or derivatives thereof from O-phosphoserine using the same

The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydryla...

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Bibliographische Detailangaben
Hauptverfasser: KIM KHIE VON, SIN JONG JUK, UM KHIE VON, CHANG DZIN SOOK, SONG BIEONG CHEOL, DZO DZAE KHIUN, KIM SOL, SHIN SOO AN, DZKHON SUNG KHOO, JANG EUN BIN, LI KIOUNG MIN, BAE KHIUN AE
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.