Preparation for feather keratin and sodium alginate composite polymer double-sensitive hydrogel and application therefore as drug carrier

The invention provides preparation of feather keratin and sodium alginate composite polymer double-sensitive hydrogel and belongs to the field of composite materials and the field of biotechnology. The feather keratin and the sodium alginate are taken as natural polymer raw materials, N-isopropylacrylamide is taken as a thermosensitive monomer, N,N-methylene bisacrylamide is taken as a cross-linking agent, ammonium persulfate or ammonium persulfate potassium is taken as an initiator, and an interpenetrating network technology is adopted for preparation. The prepared keratin and sodium alginate composite polymer hydrogel has a microcellular structure and temperature and pH sensibility, is good in biocompatibility, and can realize controlled release for small molecule drugs. An in-vitro drug release performance experiment result shows that by using the acid sensitivity of the feather keratin and sodium alginate composite polymer double-sensitive hydrogel, the controlled release of drug molecules can be realized, so that the feather keratin and sodium alginate composite polymer double-sensitive hydrogel can be applied to the field of biomedicine as a drug carrier.