Application of N-thiazole benzoxazinone derivatives serving as neuraminidase inhibitors

The invention relates to 3-[5-(1,2,4-triazole-1-yl) thiazole-2-yl] benzoxazinone having a chemical structure formula I shown in the specification or salts thereof; in the formula, R is selected from C1-C2 alkyl and C3-C4 linear chain or C3-C4 branched alkyl; X1 is selected from H, deuterium, methyl, ethyl, C3-C4 linear chain alkyl or C3-C4 branched alkyl, F, Cl, Br or I; X2 is selected from H, deuterium, methyl, ethyl and C3-C4 linear chain alkyl or C3-C4 branched alkyl; X3 is selected from H, deuterium, methyl, ethyl, C3-C4 linear chain alkyl or C3-C4 branched alkyl, F, Cl, Br, I or nitro; X4 is selected from H, deuterium, methyl, ethyl and C3-C4 linear chain alkyl or C3-C4 branched alkyl; and the salts of 3-[5-(1,2,4-triazole-1-yl) thiazole-2-yl] benzoxazinone are selected from hydrochlorides, hydrobromides, sulfates, nitrates, phosphates, mesylates, benzene sulfonates, p-toluene sulfonic acid salts, malates, lactates, succinates, maleates or fumarates. The invention provides the application of 3-[5-(1,2,4-triazole-1-yl) thiazole-2-yl] benzoxazinone or the salts thereof in preparation of anti-neuraminidase inhibitors.