Preparation method and application of vernonia anthelmintica phenolic acid part
The invention relates to a preparation method and an application of a vernonia anthelmintica phenolic acid part. The preparation method comprises the following steps of smashing dry vernonia anthelmintica fruits; extracting the drying vernonia anthelmintica fruits by using organic solvent; and perfo...
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| creator | LI HAORONG AJIAIKEBAIER AISA ABULAJIANG TULAKE MAI DINA ZULIPIYA MAIMAITI XIN XUELEI |
| description | The invention relates to a preparation method and an application of a vernonia anthelmintica phenolic acid part. The preparation method comprises the following steps of smashing dry vernonia anthelmintica fruits; extracting the drying vernonia anthelmintica fruits by using organic solvent; and performing resin separation and purification to obtain vernonia anthelmintica extracts which mainly comprise a phenolic acid compound. The content of phenolic acid in the vernonia anthelmintica phenolic acid part is 20%-99% in percentage by mass. The vernonia anthelmintica phenolic acid part also comprises the following main active ingredients in percentage by mass: 3-26% of 3, 4-dicaffeoyl-quinic acid, 5-34% of 3, 5-dicaffeoyl-quinic acid and 5-40% of 4, 5-dicaffeoyl-quinic acid. A preliminary experiment proves that the vernonia anthelmintica phenolic acid part obtained by the method has effects of increasing melanocyte in hair follicle and promoting melanogenesis and can be used for treating leukoderma. The preparation method is simple in technology and low in production cost; effective ingredients are stable; and the quality is easy to control. By the preparation method and the application of the vernonia anthelmintica phenolic acid part, a novel medicinal part and compounds are provided for treatment of the leukoderma. |
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The preparation method comprises the following steps of smashing dry vernonia anthelmintica fruits; extracting the drying vernonia anthelmintica fruits by using organic solvent; and performing resin separation and purification to obtain vernonia anthelmintica extracts which mainly comprise a phenolic acid compound. The content of phenolic acid in the vernonia anthelmintica phenolic acid part is 20%-99% in percentage by mass. The vernonia anthelmintica phenolic acid part also comprises the following main active ingredients in percentage by mass: 3-26% of 3, 4-dicaffeoyl-quinic acid, 5-34% of 3, 5-dicaffeoyl-quinic acid and 5-40% of 4, 5-dicaffeoyl-quinic acid. A preliminary experiment proves that the vernonia anthelmintica phenolic acid part obtained by the method has effects of increasing melanocyte in hair follicle and promoting melanogenesis and can be used for treating leukoderma. The preparation method is simple in technology and low in production cost; effective ingredients are stable; and the quality is easy to control. By the preparation method and the application of the vernonia anthelmintica phenolic acid part, a novel medicinal part and compounds are provided for treatment of the leukoderma.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150812&DB=EPODOC&CC=CN&NR=104825519A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150812&DB=EPODOC&CC=CN&NR=104825519A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI HAORONG</creatorcontrib><creatorcontrib>AJIAIKEBAIER AISA</creatorcontrib><creatorcontrib>ABULAJIANG TULAKE</creatorcontrib><creatorcontrib>MAI DINA</creatorcontrib><creatorcontrib>ZULIPIYA MAIMAITI</creatorcontrib><creatorcontrib>XIN XUELEI</creatorcontrib><title>Preparation method and application of vernonia anthelmintica phenolic acid part</title><description>The invention relates to a preparation method and an application of a vernonia anthelmintica phenolic acid part. The preparation method comprises the following steps of smashing dry vernonia anthelmintica fruits; extracting the drying vernonia anthelmintica fruits by using organic solvent; and performing resin separation and purification to obtain vernonia anthelmintica extracts which mainly comprise a phenolic acid compound. The content of phenolic acid in the vernonia anthelmintica phenolic acid part is 20%-99% in percentage by mass. The vernonia anthelmintica phenolic acid part also comprises the following main active ingredients in percentage by mass: 3-26% of 3, 4-dicaffeoyl-quinic acid, 5-34% of 3, 5-dicaffeoyl-quinic acid and 5-40% of 4, 5-dicaffeoyl-quinic acid. A preliminary experiment proves that the vernonia anthelmintica phenolic acid part obtained by the method has effects of increasing melanocyte in hair follicle and promoting melanogenesis and can be used for treating leukoderma. The preparation method is simple in technology and low in production cost; effective ingredients are stable; and the quality is easy to control. By the preparation method and the application of the vernonia anthelmintica phenolic acid part, a novel medicinal part and compounds are provided for treatment of the leukoderma.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAPKEotSCxKLMnMz1PITS3JyE9RSMwD4oKCnMxkiHB-mkJZalFefl5mIlCuJCM1JzczrwQoq1CQkZqXD1SnkJicmaIANKeEh4E1LTGnOJUXSnMzKLq5hjh76KYW5MenFhckJqfmpZbEO_sZGphYGJmaGlo6GhOjBgCTDTdb</recordid><startdate>20150812</startdate><enddate>20150812</enddate><creator>LI HAORONG</creator><creator>AJIAIKEBAIER AISA</creator><creator>ABULAJIANG TULAKE</creator><creator>MAI DINA</creator><creator>ZULIPIYA MAIMAITI</creator><creator>XIN XUELEI</creator><scope>EVB</scope></search><sort><creationdate>20150812</creationdate><title>Preparation method and application of vernonia anthelmintica phenolic acid part</title><author>LI HAORONG ; AJIAIKEBAIER AISA ; ABULAJIANG TULAKE ; MAI DINA ; ZULIPIYA MAIMAITI ; XIN XUELEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN104825519A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2015</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LI HAORONG</creatorcontrib><creatorcontrib>AJIAIKEBAIER AISA</creatorcontrib><creatorcontrib>ABULAJIANG TULAKE</creatorcontrib><creatorcontrib>MAI DINA</creatorcontrib><creatorcontrib>ZULIPIYA MAIMAITI</creatorcontrib><creatorcontrib>XIN XUELEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI HAORONG</au><au>AJIAIKEBAIER AISA</au><au>ABULAJIANG TULAKE</au><au>MAI DINA</au><au>ZULIPIYA MAIMAITI</au><au>XIN XUELEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method and application of vernonia anthelmintica phenolic acid part</title><date>2015-08-12</date><risdate>2015</risdate><abstract>The invention relates to a preparation method and an application of a vernonia anthelmintica phenolic acid part. The preparation method comprises the following steps of smashing dry vernonia anthelmintica fruits; extracting the drying vernonia anthelmintica fruits by using organic solvent; and performing resin separation and purification to obtain vernonia anthelmintica extracts which mainly comprise a phenolic acid compound. The content of phenolic acid in the vernonia anthelmintica phenolic acid part is 20%-99% in percentage by mass. The vernonia anthelmintica phenolic acid part also comprises the following main active ingredients in percentage by mass: 3-26% of 3, 4-dicaffeoyl-quinic acid, 5-34% of 3, 5-dicaffeoyl-quinic acid and 5-40% of 4, 5-dicaffeoyl-quinic acid. A preliminary experiment proves that the vernonia anthelmintica phenolic acid part obtained by the method has effects of increasing melanocyte in hair follicle and promoting melanogenesis and can be used for treating leukoderma. The preparation method is simple in technology and low in production cost; effective ingredients are stable; and the quality is easy to control. By the preparation method and the application of the vernonia anthelmintica phenolic acid part, a novel medicinal part and compounds are provided for treatment of the leukoderma.</abstract><oa>free_for_read</oa></addata></record> |
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| title | Preparation method and application of vernonia anthelmintica phenolic acid part |
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