Benzoate of 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative, and preparation method and pharmaceutical composition thereof

Benzoate of 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative, and preparation method and pharmaceutical composition thereof

The invention discloses a benzoate of a 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative, and a preparation method and a pharmaceutical composition thereof. Structural formula of the benzoate of the 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative is represented by formula II. Th...

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Bibliographische Detailangaben
Hauptverfasser: CHEN SHUJUN, CAI ZEMIAN, XIE FUSHENG, ZHI JIANQIONG, TAN SONGDE, WANG WEIBO, LI TONGSHUANG
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention discloses a benzoate of a 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative, and a preparation method and a pharmaceutical composition thereof. Structural formula of the benzoate of the 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative is represented by formula II. The benzoate of the 3-(3-aminopiperidine-1-yl)-5-oxo-1,2,4-triazine derivative is suitable for development of an excellent medicine used for treating type-2 diabetes, and is applied to clinical practice; product quality is ensured effectively; and excellent guarantee is provided for drug application safety and effectiveness. The preparation method is simple in technology; cost is relatively low; yield and purity are both high; and the preparation method is suitable for large-scale industrial production.