Process for preparing antiviral agent

Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.

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Bibliographische Detailangaben
Hauptverfasser:	VEMISHETTI PURUSHOTHAM, KUCERA DAVID J, PRASAD SIVA JOSYULA, PATEL SUNIL S, SHI ZHONGPING, LIANG JING, RIJHWANI SUSHIL K, SINGH AMBARISH K, BIEN JEFFREY T, LEWIS CHARLES, ZHOU MAOTANG X, BANERJEE AMIT, THOTTATHIL JOHN, CHEN CHUNG-PIN H, PATEL RAMESH N, STOJANOVIC MILAN, PENDRI YADAGIRI R, CHAN YEUNG YU, WANG SHAOPENG, EVANS JEFFREY M, POLNIASZEK RICHARD P, KRONENTHAL DAVID R, POWERS GERALD L, KRISHNAMURTY DHILEEPKUMAR
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.