Temperature-sensitive controlled-release pharmaceutical composition of taxane drugs

The invention relates to a temperature-sensitive controlled-release pharmaceutical composition of taxane drugs. Specifically speaking, the invention relates to the pharmaceutical composition which comprises taxane drugs, chitosan, sodium beta-glycerophosphate, ethanol and water, and further relates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHEN XIJING, QU CHANGHAI, LI DAKUI, TANG WEISONG, FENG FENGYI, ZHAO DI, LI CUIYUN, MEI DAN, WANG ZIHOU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a temperature-sensitive controlled-release pharmaceutical composition of taxane drugs. Specifically speaking, the invention relates to the pharmaceutical composition which comprises taxane drugs, chitosan, sodium beta-glycerophosphate, ethanol and water, and further relates to a preparation method for the pharmaceutical composition. The pharmaceutical composition can be used for preparation of anticancer drugs. In particular, the anticancer drugs are applied to treatment of malignant tumors or prevention of recurrence after operation through a stereotaxical injection approach and can be cooperatively used with radiotherapy and traditional Chinese medicine.