Determining a dominant hand of a user of a computing device

In one example, a method includes determining, by a computing device, a plurality of features. Each feature from the plurality of features may be usable to determine a dominant hand of a user of the computing device. The method also includes receiving, by the computing device, a plurality of input values, each input value from the plurality of input values corresponding to the respective plurality of features, and determining, using a probabilistic model and based at least in part on at least one input value from the plurality of input values corresponding to the respective feature from the plurality of features, a hand of the user as a dominant hand of the user. The method also includes generating, based at least in part on the determined dominant hand of the user, a graphical user interface for display at a presence-sensitive display operatively coupled to the computing device.